Suggested Journal Club Articles will be posted here as they are made available. The selection of papers for review at Journal Club is overseen by the Chief Residents of the RCPS and CFPC Emergency Medicine training programs and is based on proposals by EM faculty and residents. If you come across a paper you feel merits consideration for review at Journal Club, please use the automated submission form to notify us of this.
Submitted Jan 2018
Adjunctive Glucocorticoid Therapy in Patients with Septic Shock – D. Ting
Note: Essentially a negative trial, but discussion provoking on what (if anything) to offer in refractory septic shock.
Submitted Nov 2017
Oxygen Therapy in Suspected Acute Myocardial Infarction – A. Elkhalifa
Submitted Oct 2017
Is the Pelvic Examination Still Crucial in Patients Presenting to the Emergency Department With Vaginal Bleeding or Abdominal Pain When an Intrauterine Pregnancy Is Identified on Ultrasonography? A Randomized Controlled Trial – R. Abu-Laban
Note: Raises an important clinical question, and also a forum for discussing clinical and methodologic issues surrounding equivalence trials.
Submitted Sept 2017
Randomized Trial of Icatibant for Angiotensin-Converting Enzyme Inhibitor-Induced Upper Airway Angioedema – J. Taylor
Note: Good negative trial, in follow up to NEJM positive trial for the same medication. Interesting that this negative trial was published in a much smaller journal. A Randomized Trial of Icatibant in ACE-Inhibitor–Induced Angioedema.
Submitted June 2017
Simplified diagnostic management of suspected pulmonary embolism (the YEARS study): a prospective, multicentre, cohort study – D. Ting
Note: Interesting multicenter study looking at using a higher D-dimer threshold (<1000) for patients at low risk of PE, finding that it may be used successfully and reduce testing. Similar study ongoing at McMaster in the patient recruitment phase.
Submitted April 2017
Trial of Decompressive Craniectomy for Traumatic Intracranial Hypertension – B. Tuyp
Note: Although decompressive craniectomy is not a treatment provided by Emergency Physicians or in the Emergency Department, it is nonetheless important to know the natural history of severe traumatic brain injury. Moreover, this is a landmark trial with which all physicians treating severe traumatic brain injury should be familiar with. Finally, the study results are interesting and conversation provoking in that this trial can be seen as both positive (favouring decompression) or negative depending on how you define a good outcome